With the global surge in the use of electronic cigarettes, there is a corresponding increase in the consumption of e-liquid. Howev-er, different regions and countries impose varying regulatory re-quirements concerning the types and concentrations of flavorings added to electronic liquids (e-liquids). Analyzing the flavorings in e-liquids poses a challenge due to their substantial content of pro-pylene glycol, glycerol solvent, and nicotine as a matrix.
Conventional methods such as traditional solvent extraction and simultaneous distillation/extraction necessitate the use of sol-vents, leading to time-consuming, labor-intensive, and cumber-some procedures. Additionally, the sensitivity of solid phase mi-croextraction is limited, and headspace analysis may be affected by solvent interference.
In response to these challenges, Stir Bar Sorptive Extraction (SBSE) emerges as a modern, green, and solvent-free sample extraction technology. Renowned for its efficiency, high sensitivity, and us-er-friendly operation, SBSE proves particularly effective in extract-ing volatile flavor and aroma components from e-liquids. The an-alytical process involves utilizing a Cooled Inlet System, thermal desorption, and gas chromatography-mass spectrometry for the analysis and identification of volatile flavor and aroma compounds in e-liquids. The AromaOffice2D flavor compounds database soft-ware is then employed to process the GC-MS data, enhancing the precision and efficiency of flavor compound identification.